Relative biological effectiveness (RBE) and dose rate dependent ratio of translocation to dicentric chromosome yield in 252Cf neutrons
نویسندگان
چکیده
منابع مشابه
RBE-dose relations for neutrons and pions.
From cellular radiosensitivity parameters and theoretical particle-energy spectra in tissue, of the secondary particles from neutron and negative pion irradiations, RBE-Dose relations have been calculated. The theoretical results are compared with clinical and radiobiological data for normal tissue, tumours and cells in culture. Formulae for calculation, cellular parameters and the needed prope...
متن کاملNeutron energy-dependent initial DNA damage and chromosomal exchange.
This study was undertaken to investigate the biological effect of monoenergetic neutrons on human lymphocyte DNA and chromosomes. Monoenergetic neutrons of 2.3, 1.0, 0.79, 0.57, 0.37 and 0.186 MeV were generated, and 252Cf neutrons and 60Co gamma-rays were also used for comparison. Biological effect was evaluated two ways. The RBE values with the comet assay were estimated as 6.3 and 5.4 at 0.3...
متن کاملRapid MCNP simulation of DNA double strand break (DSB) relative biological effectiveness (RBE) for photons, neutrons, and light ions.
To account for particle interactions in the extracellular (physical) environment, information from the cell-level Monte Carlo damage simulation (MCDS) for DNA double strand break (DSB) induction has been integrated into the general purpose Monte Carlo N-particle (MCNP) radiation transport code system. The effort to integrate these models is motivated by the need for a computationally efficient ...
متن کاملRelative Biological Effectiveness (RBE) of 131I Radiation Relative to 60Co Gamma Rays
OBJECTIVE To assess relative biological effectiveness (RBE) of (131)I radiation relative to (60)Co gamma rays in glioblastoma spheroid cells. MATERIALS AND METHODS : In this experimental study, glioblastoma spheroid cells were exposed to (131)I radiation and (60)Co gamma rays. Radiation induced DNA damage was evaluated by alkaline comet assay. Samples of spheroid cells were treated by radiati...
متن کاملrelative biological effectiveness (rbe) of 131i radiation relative to 60co gamma rays
objective: to assess relative biological effectiveness (rbe) of 131i radiation relative to 60co gamma rays in glioblastoma spheroid cells. materials and methods: in this experimental study, glioblastoma spheroid cells were exposed to 131i radiation and 60co gamma rays. radiation induced dna damage was evaluated by alkaline comet assay. samples of spheroid cells were treated by radiation from 13...
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ژورنال
عنوان ژورنال: Indian Journal of Science and Technology
سال: 2009
ISSN: 0974-6846,0974-5645
DOI: 10.17485/ijst/2009/v2i1.1